Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 3/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.48 |
| ▸ | FGF1 | P05230 | 5/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | VDR | P11473 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | FGF2 | P09038 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458288 | 1.00 | CYP2D6 (0.54) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11469565 | 1.00 | CYP2D6 (0.54) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11467678 | 1.00 | CYP2D6 (0.54) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11467679 | 1.00 | CYP2D6 (0.54) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11458287 | 1.00 | CYP2D6 (0.54) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11459523 | 0.88 | VDR (0.61) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11470503 | 0.88 | VDR (0.61) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11459524 | 0.88 | VDR (0.61) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11458228 | 0.82 | CYP2D6 (0.53) | CYP2D6CYP2C19CDC25APOLA1INPP5D | |
| SCHEMBL11459235 | 0.79 | CYP2D6 (0.67) | CYP2D6CYP2C19CDC25APOLA1INPP5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183923-A | 3-ALKANESULFONYLOXYAZETIDINES | SCHERING CORPORATION (US) | 1980-01-15 | — | — | US | disclosed |