Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469833 | 1.00 | KDM4E (0.80) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28632999 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28637135 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL11344094 | 0.90 | TRPV1 (0.79) | KDM4EALDH1A1KMT2ATRPV1BCHE | |
| SCHEMBL3121290 | 0.88 | KDM4E (0.97) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL3121297 | 0.88 | KDM4E (0.97) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28652743 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL29967007 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28644016 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28924931 | 0.85 | APP (0.84) | KDM4EALDH1A1KMT2AMEN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189484-A | Antihypertensive quinazoline derivatives | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-19 | — | — | US | disclosed |