Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | FDPS | P14324 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644016 | 1.00 | KDM4E (0.61) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL28632999 | 0.87 | KDM4E (0.66) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL11469832 | 0.86 | KDM4E (0.80) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL11469833 | 0.86 | KDM4E (0.80) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL28652743 | 0.84 | KDM4E (0.62) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL28924931 | 0.82 | APP (0.84) | KDM4EKMT2AALDH1A1APPMEN1 | |
| SCHEMBL10966941 | 0.81 | KDM4E (0.58) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL12336758 | 0.81 | NFE2L2 (0.72) | KDM4EKMT2AALDH1A1TDP1APP | |
| SCHEMBL21715528 | 0.81 | KDM4E (0.69) | KDM4EKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL19695927 | 0.81 | FDPS (0.73) | KDM4EKMT2AALDH1A1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |