Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234082 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EFDPSALDH1A3 | |
| SCHEMBL20810421 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EDHFRTACR2 | |
| SCHEMBL26261539 | 0.77 | NPC1 (0.53) | ALDH1A1KDM4EALDH1A3MAPTLMNA | |
| SCHEMBL3861852 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EDHFRTACR2 | |
| SCHEMBL9829442 | 0.74 | TDP1 (0.48) | ALDH1A1KDM4EHPGDTDP1MAPT | |
| SCHEMBL3864555 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EDHFRTACR2 | |
| SCHEMBL4363481 | 0.74 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EDHFRTACR2 | |
| SCHEMBL14917021 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EDHFRTACR2 | |
| SCHEMBL27458779 | 0.72 | HRH4 (0.59) | ALDH1A1GAAKDM4EHPGDL3MBTL1 | |
| SCHEMBL7926375 | 0.71 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4184977-A | WHITENING | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| EP-0000346-B1 | QUINOXALINE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS BRIGHTENERS FOR ORGANIC MATERIALS, AND THE MATERIALS BRIGHTENED THEREWITH | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0000346-A1 | Quinoxaline compounds, process for their manufacture and their use as brighteners for organic materials, and the materials brightened therewith | BAYER AG (DE) | 1979-01-24 | — | — | EP | disclosed |