Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420220 | 0.83 | ALDH1A1 (0.58) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL6815196 | 0.81 | MEN1 (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24335864 | 0.78 | ALDH1A1 (0.56) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL29580720 | 0.78 | ALDH1A1 (0.56) | KDM4ENPC1MITFTHRBMAPK1 | |
| Hydrochloric Acid SCHEMBL9488289 | 0.77 | RAD52 (0.62) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL10684407 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL17414141 | 0.76 | ALDH1A1 (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29928867 | 0.75 | NPC1 (0.53) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL28391565 | 0.75 | NPC1 (0.53) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL4193257 | 0.75 | ALDH1A1 (0.55) | KDM4ENPC1MITFTHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | disclosed |