Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.52 |
| ▸ | KDM5A | P29375 | 7/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463687 | 0.78 | EGLN2 (0.58) | KDM4CKDM5BKDM5ANPC1LMNA | |
| SCHEMBL10761987 | 0.78 | KDM4E (0.41) | KDM4CKDM5BKDM5AKDM4APDE4D | |
| SCHEMBL30740531 | 0.77 | KDM5A (0.52) | KDM4CKDM5BKDM5AKDM4AKMO | |
| SCHEMBL940183 | 0.77 | KDM5A (0.52) | KDM4CKDM5BKDM5AKDM4AKMO | |
| SCHEMBL3155417 | 0.76 | KDM4E (0.54) | KDM4CKDM5BKDM5AKDM4APDE4D | |
| SCHEMBL11473783 | 0.74 | EGLN2 (0.68) | — | |
| SCHEMBL5946455 | 0.74 | DYRK3 (0.47) | PDE4DDYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL5946454 | 0.73 | EGLN2 (0.39) | PDE4DNPC1LMNAMAPTRAB9A | |
| SCHEMBL6071500 | 0.71 | EGLN2 (0.51) | PDE4DMAPTRAB9ADYRK1AFYN | |
| SCHEMBL21310947 | 0.71 | DYRK1A (0.50) | KDM4CKDM5BKDM5AKDM4AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4236005-A | ANTIANXIETY | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4178449-A | Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |