Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 14/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481920 | 0.90 | PARP1 (0.53) | CHEK2ADORA2AADORA2BPARP1 | |
| SCHEMBL11481631 | 0.88 | PARP1 (0.52) | CHEK2ADORA2AADORA2BPARP1 | |
| SCHEMBL11485417 | 0.85 | PARP1 (0.52) | CHEK2IKBKBPARP1 | |
| SCHEMBL11473195 | 0.85 | CHEK2 (0.46) | CHEK2PKN1PKN2PARP1 | |
| SCHEMBL11473953 | 0.85 | CHEK2 (0.51) | CHEK2PARP1 | |
| SCHEMBL11474673 | 0.85 | CHEK2 (0.52) | CHEK2IKBKBPARP1 | |
| SCHEMBL11479983 | 0.85 | PIN1 (0.56) | CHEK2IKBKBPARP1 | |
| SCHEMBL11472312 | 0.83 | PKN1 (0.51) | CHEK2PKN1PKN2MKNK2PARP1 | |
| SCHEMBL11472418 | 0.82 | PARP1 (0.60) | CHEK2PKN1PKN2PARP1 | |
| SCHEMBL11470177 | 0.81 | PARP1 (0.55) | CHEK2IKBKBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218457-A | ANTICANCER ACTIVITY AND IMMUNOSTIMULATING ACTIVITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-08-19 | — | — | US | disclosed |