Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11314659 | 0.99 | TSHR (0.56) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL3074195 | 0.88 | TSHR (0.56) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL3074194 | 0.88 | TSHR (0.56) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL11464361 | 0.82 | TSHR (0.54) | TSHRKDM4ECYP2C19ATMHSF1 | |
| Hydrochloric Acid SCHEMBL11318009 | 0.81 | TSHR (0.53) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13576478 | 0.79 | TSHR (0.77) | TSHRALDH1A1HTTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3054925 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAMAPTCYP1A2 | |
| SCHEMBL6548832 | 0.74 | KDM4E (0.60) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL6548825 | 0.74 | KDM4E (0.60) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL11470041 | 0.74 | TSHR (0.53) | TSHRALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187220-A | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1980-02-05 | — | — | US | claimed |