Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23552448 | 0.79 | SRC (0.49) | MEN1KMT2AHPGDTDP1ALOX15 | |
| SCHEMBL3633768 | 0.77 | MEN1 (0.47) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL622329 | 0.74 | MAPT (0.61) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL3607515 | 0.73 | TDP1 (0.57) | MEN1KMT2AHPGDTDP1ALOX15 | |
| SCHEMBL4325061 | 0.72 | EPHX2 (0.52) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL27762442 | 0.72 | TDP1 (0.48) | MEN1KMT2ATDP1MAPTERN1 | |
| SCHEMBL16731569 | 0.72 | KMT2A (0.49) | MEN1KMT2AHPGDTDP1ALOX15 | |
| SCHEMBL10955526 | 0.72 | ALDH1A1 (0.48) | HPGDMAPTALDH1A1 | |
| SCHEMBL15544882 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL838576 | 0.71 | KMT2A (0.48) | MEN1KMT2AHPGDTDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188395-A | 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |