Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093066 | 0.83 | TAAR1 (0.57) | KMT2AALDH1A1 | |
| SCHEMBL11473695 | 0.82 | ALDH1A1 (0.50) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11474307 | 0.81 | HRH3 (0.43) | LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6477285 | 0.81 | TAAR1 (0.55) | KMT2AALDH1A1 | |
| SCHEMBL11481171 | 0.80 | KMT2A (0.53) | LMNAHSD17B10KMT2AALDH1A1 | |
| SCHEMBL18773733 | 0.80 | AOC3 (0.56) | LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL21592421 | 0.80 | ALDH1A1 (0.47) | LMNAHSD17B10KMT2AALDH1A1 | |
| SCHEMBL6411856 | 0.80 | TAAR1 (0.60) | KMT2A | |
| SCHEMBL69746 | 0.78 | FFAR1 (0.81) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL14412444 | 0.77 | AOC3 (0.59) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238506-A | SECONDARY OR TERTIARY AMIDE-SUBSTITUTED | BOEHRINGER MANNHEIM GMBH (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4113871-A | HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-09-12 | — | — | US | disclosed |