Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308315 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL13532554 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28414469 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL13684308 | 0.79 | MAPK1 (0.37) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL21846702 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7802041 | 0.75 | KDM4E (0.45) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7796000 | 0.75 | KDM4E (0.45) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL17532417 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7804741 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7802817 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8400730-B2 | Multistage gasket | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20110038077-A1 | MULTISTAGE GASKET | BRIDGESTONE CORPORATION (JP) | 2011-02-17 | — | — | US | disclosed |