Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460158 | 0.90 | MRGPRX4 (0.41) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL11480934 | 0.87 | MAPT (0.53) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL11472953 | 0.84 | MAPT (0.50) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL11463655 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL11471667 | 0.79 | MRGPRX4 (0.43) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11461852 | 0.77 | ELANE (0.42) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL10598949 | 0.77 | LMNA (0.51) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL10599595 | 0.77 | LMNA (0.51) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL10955599 | 0.76 | MAPT (0.66) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL10341808 | 0.76 | MAPT (0.58) | MAPTMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |