Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633074 | 0.89 | AR (0.67) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL94938 | 0.82 | AR (0.69) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL3661785 | 0.81 | AR (0.69) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL634133 | 0.79 | AR (0.65) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL11463857 | 0.78 | AR (0.59) | ARMEN1LMNATP53CYP1A2 | |
| Nilutamide SCHEMBL12670 | 0.78 | AR (1.00) | ARMEN1LMNATP53CYP1A2 | |
| Nilutamide SCHEMBL1462011 | 0.78 | AR (1.00) | ARMEN1LMNATP53CYP1A2 | |
| Nilutamide SCHEMBL29351021 | 0.78 | AR (1.00) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL1875673 | 0.78 | AR (0.66) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL1880533 | 0.78 | AR (0.66) | ARMEN1LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234736-A | FLUOROPHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1980-11-18 | — | — | US | disclosed |