Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093423 | 0.86 | AR (0.66) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL17571938 | 0.86 | AR (0.64) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL11481148 | 0.84 | AR (0.51) | ARKMT2AMEN1LMNAALOX12 | |
| SCHEMBL16879171 | 0.82 | AR (0.56) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL632634 | 0.82 | AR (0.67) | AR | |
| SCHEMBL13166747 | 0.82 | AR (0.56) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL11079218 | 0.82 | AR (1.00) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL633074 | 0.81 | AR (0.67) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL11474265 | 0.81 | AR (0.64) | ARKMT2AMEN1LMNATP53 | |
| SCHEMBL11461814 | 0.81 | AR (0.64) | ARKMT2AMEN1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242745-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | Sanofi-Aventis (FR) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
| US-4234736-A | FLUOROPHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1980-11-18 | — | — | US | disclosed |
| EP-0017976-A2 | Process for preparing imidazole derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-10-29 | — | — | EP | disclosed |