Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483450 | 0.90 | HSD17B10 (0.32) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL11357604 | 0.90 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL10388786 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL11280943 | 0.86 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8008323 | 0.86 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL940389 | 0.85 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL725088 | 0.83 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL11489974 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL11490957 | 0.82 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL27831962 | 0.82 | TSHR (0.38) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204972-A | Hydraulic fluids comprising nitrogen-containing boric acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-27 | — | — | US | disclosed |