Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476352 | 0.84 | P2RY1 (0.44) | KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL15596971 | 0.81 | NPC1 (0.38) | SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL11358850 | 0.78 | L3MBTL1 (0.48) | SMN1; SMN2KMT2APTK2ABL1ADORA3 | |
| SCHEMBL2642653 | 0.78 | GRM5 (0.44) | SMN1; SMN2KMT2AADORA3L3MBTL1ADORA2A | |
| SCHEMBL11350463 | 0.78 | L3MBTL1 (0.62) | SMN1; SMN2KMT2AABL1L3MBTL1KDM4E | |
| SCHEMBL2642974 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APTK2ABL1ADORA3 | |
| SCHEMBL2642609 | 0.77 | PIK3CG (0.53) | SMN1; SMN2KMT2AABL1ADORA3L3MBTL1 | |
| SCHEMBL2642652 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APTK2ABL1ADORA3 | |
| SCHEMBL2642608 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APTK2ABL1ADORA3 | |
| SCHEMBL2642976 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APTK2ABL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148904-A | 2-HALO-4-CARBOXAMIDE- OR CARBOXIMIDOTHIAZOLES | JOHN WYETH & BROTHER LIMITED (GB) | 1979-04-10 | — | — | US | claimed |
| CN-102964312-A | 4-tertiary butyl-5-(1-aryl-2-nitre ethyl)-2-acylamino thiazole as well as preparation method and application thereof | UNIV HUNAN | 2013-03-13 | — | — | CN | disclosed |
| CN-102942536-A | 4-tertiary butyl-5-(1-aryl-2-ethyl nitrate)-2-amido-thiazole with insecticidal activity and preparation method thereof | UNIV HUNAN | 2013-02-27 | — | — | CN | disclosed |
| CN-102936229-A | 4-tertiary butyl-5-benzyl-2-acetyl aminothiazole with insecticidal activity and preparation method | UNIV HUNAN | 2013-02-20 | — | — | CN | disclosed |
| US-4183854-A | ANTIULCER OR ANTISECRETORY AGENT FOR MAMMALS | JOHN WYETH & BROTHER LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4148904-A | 2-HALO-4-CARBOXAMIDE- OR CARBOXIMIDOTHIAZOLES | JOHN WYETH & BROTHER LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |