SCHEMBL1147673

SCHEMBL1147673

C/C(O)=C/CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350732 1.00
SCHEMBL8612723 1.00
Hydrogen Peroxide SCHEMBL31511442 0.77
SCHEMBL12189737 0.73 KMT2A (0.71)
SCHEMBL115620 0.72
SCHEMBL8813968 0.72 KMT2A (0.55)
SCHEMBL9720523 0.72
SCHEMBL9720524 0.72
Alcohol SCHEMBL10454878 0.72
SCHEMBL28730756 0.69 ALOX15 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1654289-B1 POLYSIALIC ACID DERIVATIVES LIPOXEN TECHNOLOGIES LTD (GB) 2007-10-03 EP claimed
US-20060270830-A1 Polysialic acid derivatives OPKO PHARMACEUTICALS, LLC 2006-11-30 US claimed
US-9517203-B2 Polymer particle delivery compositions and methods of use MEDIV AS, LLC (US) 2016-12-13 US disclosed
US-8765164-B2 Poly(ester urea) polymers and methods of use Carpenter, Kenneth W. (US) 2014-07-01 US disclosed
EP-1833779-B1 Process for the preparation of 2-butene-1,4-diol DSM IP ASSETS BV (NL) 2014-05-07 EP disclosed
US-8652504-B2 Solid polymer delivery compositions and methods for use thereof MEDIVAS, LLC (US) 2014-02-18 US disclosed
US-20120328706-A1 POLYMER PARTICLE DELIVERY COMPOSITIONS AND METHODS OF USE MEDIVAS, LLC (US) 2012-12-27 US disclosed
US-8163269-B2 Bioactive stents for type II diabetics and methods for use thereof MEDIVAS, LLC 2012-04-24 US disclosed
US-20110027379-A1 Oligo-Ethylene Glycol-Based Polymer Compositions and Methods of Use CORNELL UNIVERSITY 2011-02-03 US disclosed
EP-2227223-A2 OLIGO-ETHYLENE GLYCOL-BASED POLYMER COMPOSITIONS AND METHODS OF USE Medivas, LLC (US) 2010-09-15 EP disclosed
EP-1439177-B1 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane UNIV EMORY (US) 2010-05-26 EP disclosed
US-5814639-A TREATING AIDS EMORY UNIVERSITY (US) 1998-09-29 US disclosed
US-5700937-A LIPOSOME SUSPENSION FOR TREATMENT OF AIDS EMORY UNIVERSITY (US) 1997-12-23 US disclosed
EP-0781136-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1997-07-02 EP disclosed
WO-1996007413-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-03-14 WO disclosed
EP-0575482-A1 ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE EMORY UNIVERSITY (US) 1993-12-29 EP disclosed
US-5210085-A Treating HIV infections EMORY UNIVERSITY (US) 1993-05-11 US disclosed
WO-1992014743-A2 ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE EMORY UNIVERSITY (US) 1992-09-03 WO disclosed
US-4436841-A Single-phase, storage-stable polyol compositions containing salts and the use thereof in the production of polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1984-03-13 US disclosed
US-4289915-A Halogenated polyhydroxy compounds and their derivatives PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1981-09-15 US disclosed