Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776948 | 0.81 | HPGD (0.46) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5776944 | 0.81 | HPGD (0.46) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11482052 | 0.76 | HPGD (0.52) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11482047 | 0.76 | HPGD (0.52) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11475019 | 0.74 | HPGD (0.55) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5776078 | 0.74 | HPGD (0.60) | HPGDALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL10573027 | 0.74 | HPGD (0.60) | HPGDALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL5776074 | 0.74 | HPGD (0.60) | HPGDALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL5773229 | 0.74 | HPGD (0.50) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5773227 | 0.74 | HPGD (0.50) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198510-A | INTERMEDIATES FOR AROMATIC-SUBSTITUTED CARBOXYLIC ACIDS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |