Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11487101 | 0.99 | OPRM1 (0.43) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| Oxalic Acid SCHEMBL11490161 | 0.98 | OPRM1 (0.43) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL11482093 | 0.91 | OPRM1 (0.43) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL11478493 | 0.89 | OPRM1 (0.46) | OPRM1OPRD1OPRK1SLC18A3 | |
| Oxalic Acid SCHEMBL11476697 | 0.89 | OPRM1 (0.41) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL11487183 | 0.87 | KCNA3 (0.43) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11474978 | 0.86 | SLC18A3 (0.37) | SLC18A3 | |
| SCHEMBL11483205 | 0.86 | OPRM1 (0.41) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| Bromide SCHEMBL11491103 | 0.86 | KCNA3 (0.43) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11476416 | 0.84 | SLC18A3 (0.40) | OPRM1OPRD1OPRK1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | claimed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |