Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | ADK | P55263 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548369 | 0.85 | LMNA (0.55) | LMNASCN9AADORA3BRD4GSK3B | |
| SCHEMBL11818528 | 0.84 | LMNA (0.45) | LMNASCN9AADORA3BRD4ALDH1A1 | |
| SCHEMBL11822093 | 0.84 | LMNA (0.45) | LMNASCN9AADORA3BRD4ALDH1A1 | |
| SCHEMBL11724082 | 0.82 | LMNA (0.39) | LMNASCN9AADORA3BRD4GSK3B | |
| SCHEMBL11821340 | 0.80 | LMNA (0.41) | LMNASCN9AADORA3BRD4ALDH1A1 | |
| SCHEMBL3523104 | 0.79 | BRD4 (0.52) | LMNASCN9AADORA3BRD4ALDH1A1 | |
| SCHEMBL11662844 | 0.78 | LMNA (0.47) | LMNAADORA3BRD4 | |
| SCHEMBL11487326 | 0.78 | SMN1; SMN2 (0.40) | LMNAADORA3BRD4ALDH1A1HTT | |
| SCHEMBL11479612 | 0.78 | LMNA (0.53) | LMNAADORA3BRD4ALDH1A1HTT | |
| SCHEMBL11471244 | 0.78 | LMNA (0.53) | LMNAADORA3BRD4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202974-A | Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |
| US-3997564-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3978086-A | INTERMEDIATES FOR 2-AMINO-4,5-METHYLENEDIOXYBENZOPHENONIMINES | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |