Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.53 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | THPO | P40225 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270417 | 0.85 | DRD1 (0.50) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11476928 | 0.83 | DRD1 (0.74) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11480295 | 0.83 | CYP3A4 (0.42) | DRD1DRD2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11528134 | 0.79 | DRD1 (0.64) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11273006 | 0.76 | ESR1 (0.54) | DRD1DRD2HSD17B10THPOHIF1A | |
| SCHEMBL11478102 | 0.76 | DRD1 (0.58) | DRD1DRD2HSD17B10MTORTHPO | |
| Bromide SCHEMBL11462466 | 0.76 | DRD1 (0.56) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11460656 | 0.75 | DRD1 (0.76) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11460547 | 0.75 | DRD1 (0.53) | DRD1DRD2HSD17B10MTORTHPO | |
| SCHEMBL11264481 | 0.74 | DRD1 (0.46) | DRD1DRD2HSD17B10MTORTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206210-A | PARKINSON'S DISEASE | SMITHKLINE CORPORATION (US) | 1980-06-03 | — | — | US | disclosed |