Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147843 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL1147842 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL4792023 | 0.91 | MTNR1A (0.43) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL3252542 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BKDM4ECYP1A2SLC22A12 | |
| SCHEMBL3250707 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BKDM4ECYP1A2SLC22A12 | |
| SCHEMBL3252537 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BKDM4ECYP1A2SLC22A12 | |
| SCHEMBL1148173 | 0.90 | MAPT (0.43) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL1148171 | 0.90 | MAPT (0.43) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL1148169 | 0.90 | MAPT (0.43) | MTNR1AMTNR1BALDH1A1HPGDKDM4E | |
| SCHEMBL3256511 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888359-B2 | Cyclohexyl or piperidinyl carboxamide antibiotic derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-02-15 | — | — | US | disclosed |
| US-20090105232-A1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105232-A1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | CBR3, RXFP4, ODC1 | MTNR1A 1051/4885MTNR1B 1457/4885ALDH1A1 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.