Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481965 | 0.89 | OPRM1 (0.48) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| SCHEMBL11477977 | 0.89 | SMN1; SMN2 (0.46) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| Bromide SCHEMBL11487097 | 0.88 | SMN1; SMN2 (0.45) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| SCHEMBL11487177 | 0.88 | KCNA3 (0.44) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11476409 | 0.88 | SLC18A3 (0.41) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL11490159 | 0.87 | KDM4E (0.47) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| Bromide SCHEMBL11491098 | 0.87 | KCNA3 (0.43) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11491119 | 0.87 | SMN1; SMN2 (0.36) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL11490183 | 0.86 | KDM4E (0.40) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| SCHEMBL11474974 | 0.85 | SLC18A3 (0.38) | ALDH1A1KDM4ESMN1; SMN2SLC18A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |