Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002022 | 0.86 | ALDH1A1 (0.67) | MAPTALDH1A1GAATDP1TSHR | |
| SCHEMBL30038050 | 0.86 | ALDH1A1 (0.67) | MAPTALDH1A1GAATDP1TSHR | |
| SCHEMBL11240835 | 0.85 | HSD17B2 (0.65) | MAPTTRPV1ALDH1A1GAAALOX15 | |
| SCHEMBL5465814 | 0.79 | HIF1A (0.60) | MAPTALDH1A1GAATDP1TSHR | |
| SCHEMBL29129866 | 0.79 | MAPT (0.64) | MAPTEGFRALDH1A1ALOX15KMT2A | |
| SCHEMBL11459370 | 0.78 | FNTA (0.60) | MAPTALDH1A1GAATDP1HPGD | |
| SCHEMBL27529186 | 0.78 | MAPT (0.75) | MAPTALDH1A1HPGDCA1CA2 | |
| SCHEMBL16057469 | 0.77 | GAA (0.64) | MAPTTRPV1ALDH1A1GAATDP1 | |
| SCHEMBL27886589 | 0.77 | HSD17B2 (0.55) | TRPV1ALDH1A1GAATDP1TSHR | |
| SCHEMBL11478789 | 0.77 | HSD17B2 (0.49) | MAPTALDH1A1GAATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211783-A | Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-07-08 | — | — | US | disclosed |