⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575549 | 0.72 | — | — | |
| SCHEMBL224625 | 0.68 | — | — | |
| SCHEMBL15923996 | 0.63 | — | — | |
| SCHEMBL216058 | 0.61 | — | — | |
| SCHEMBL11528390 | 0.59 | USP2 (0.30) | — | |
| SCHEMBL225112 | 0.58 | — | — | |
| SCHEMBL3402274 | 0.57 | — | — | |
| SCHEMBL10628997 | 0.56 | — | — | |
| SCHEMBL15528024 | 0.53 | — | — | |
| SCHEMBL8646549 | 0.52 | USP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124518-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS INC (US) | 2024-04-18 | — | — | US | disclosed |
| US-20220017569-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS, INC. | 2022-01-20 | — | — | US | disclosed |
| EP-3492492-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | Aileron Therapeutics, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |
| EP-2342221-B1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| US-20180305400-A1 | STABILIZED COMPOUNDS HAVING SECONDARY STRUCTURE MOTIFS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-25 | — | — | US | disclosed |
| US-9951099-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170088581-A1 | STABILIZED COMPOUNDS HAVING SECONDARY STRUCTURE MOTIFS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9505801-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-29 | — | — | US | disclosed |
| US-9394336-B2 | Methods for preparing purified polypeptide compositions | AILERON THERAPEUTICS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160115204-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS, INC. | 2016-04-28 | — | — | US | disclosed |
| US-20130211046-A1 | Stabilized Compounds Having Secondary Structure Motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-08-15 | — | — | US | disclosed |
| US-8324428-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120264674-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| EP-2342221-A2 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | Aileron Therapeutics, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20110028753-A1 | Stabilized Compounds Having Secondary Structure Motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-02-03 | — | — | US | disclosed |
| US-7786072-B2 | synthesizing a peptide from a selected number of natural or non-natural amino acids; stabilized p53 donor helical peptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100210515-A1 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTICS, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010034032-A2 | METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONS | AILERON THERAPEUTIC, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-7192713-B1 | synthesizing a peptide from a selected number of natural or non-natural amino acids; stabilized p53 donor helical peptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-03-20 | — | — | US | disclosed |
| US-20060008848-A1 | synthesizing a peptide from a selected number of natural or non-natural amino acids; stabilized p53 donor helical peptides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-01-12 | — | — | US | disclosed |