Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 8/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147944 | 1.00 | SLC2A1 (0.51) | SLC2A1TRPV1KCNH2 | |
| SCHEMBL1148106 | 1.00 | SLC2A1 (0.51) | SLC2A1TRPV1KCNH2 | |
| SCHEMBL5257022 | 0.84 | KCNH2 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL5255571 | 0.84 | KCNH2 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL1147886 | 0.83 | SLC2A1 (0.55) | SLC2A1KCNH2 | |
| SCHEMBL14519826 | 0.83 | SLC2A1 (0.52) | SLC2A1KCNH2 | |
| SCHEMBL1147672 | 0.82 | TRPV1 (0.48) | TRPV1KCNH2 | |
| SCHEMBL5252947 | 0.81 | SLC2A1 (0.64) | SLC2A1KCNH2 | |
| SCHEMBL5252942 | 0.81 | SLC2A1 (0.64) | SLC2A1KCNH2 | |
| SCHEMBL1148100 | 0.80 | KCNH2 (0.68) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888359-B2 | Cyclohexyl or piperidinyl carboxamide antibiotic derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-02-15 | — | — | US | claimed |
| US-7888359-B2 | Cyclohexyl or piperidinyl carboxamide antibiotic derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-02-15 | — | — | US | disclosed |