Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.58 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CDKN1A | P38936 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489575 | 0.75 | ALDH1A1 (0.54) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL11489588 | 0.74 | HIF1A (0.65) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL1368915 | 0.74 | ALDH1A1 (0.71) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL1368527 | 0.74 | HIF1A (1.00) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL13005006 | 0.73 | BRD4 (0.78) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL14385544 | 0.73 | BRD4 (1.00) | BRD4RNASELALDH1A1HPGDKDM4E | |
| SCHEMBL17950456 | 0.73 | ALDH1A1 (1.00) | CYP1A2HIF1AALDH1A1HPGDHTT | |
| SCHEMBL13056437 | 0.71 | BRD4 (0.73) | BRD4RNASELALDH1A1HPGDKDM4E | |
| SCHEMBL4383240 | 0.70 | ALDH1A1 (0.69) | BRD4RNASELCYP1A2HIF1AALDH1A1 | |
| SCHEMBL3924265 | 0.70 | HIF1A (0.63) | BRD4RNASELCYP1A2HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |