Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488323 | 0.90 | KMT2A (0.69) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL11475018 | 0.88 | KMT2A (0.48) | KMT2AALDH1A1MEN1POLBRXRA | |
| SCHEMBL11477376 | 0.81 | KMT2A (0.71) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL11483073 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL11484201 | 0.78 | KMT2A (0.56) | KMT2AALDH1A1MEN1L3MBTL1TSHR | |
| SCHEMBL7821256 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL22831278 | 0.76 | KMT2A (0.67) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL22831282 | 0.76 | KMT2A (0.67) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL22492017 | 0.76 | KMT2A (0.67) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL11475285 | 0.76 | TDP1 (0.61) | KMT2AALDH1A1MEN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219560-A | ANTILIPEMIC AGENTS | SANDOZ, INC. (US) | 1980-08-26 | — | — | US | disclosed |