Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PDE4A | P27815 | 6/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475018 | 0.90 | KMT2A (0.48) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11482281 | 0.90 | PDE4A (0.51) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11488323 | 0.87 | KMT2A (0.69) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11488287 | 0.84 | ALDH1A1 (0.55) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11487201 | 0.83 | ALDH1A1 (0.55) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11478762 | 0.82 | L3MBTL1 (0.71) | KMT2AL3MBTL1CA1CA2MEN1 | |
| SCHEMBL11479660 | 0.81 | ALDH1A1 (0.49) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11488063 | 0.81 | HSD17B2 (0.54) | L3MBTL1HSD17B10ALDH1A1TSHR | |
| SCHEMBL11482189 | 0.78 | KMT2A (0.60) | KMT2AL3MBTL1MEN1ALDH1A1TSHR | |
| SCHEMBL10685501 | 0.77 | LMNA (0.58) | KMT2AL3MBTL1MEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219560-A | ANTILIPEMIC AGENTS | SANDOZ, INC. (US) | 1980-08-26 | — | — | US | disclosed |