⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL14634553 | 0.94 | TP53 (0.32) | — | |
| Methylene Chloride SCHEMBL59243 | 0.94 | TP53 (0.32) | — | |
| SCHEMBL9161900 | 0.73 | — | — | |
| SCHEMBL988792 | 0.73 | — | — | |
| SCHEMBL28720719 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL1686449 | 0.73 | — | — | |
| Trichlorethanol SCHEMBL88329 | 0.69 | LMNA (0.33) | — | |
| Trichlorethanol SCHEMBL16162174 | 0.69 | LMNA (0.33) | — | |
| Trichlorethanol SCHEMBL7261325 | 0.69 | LMNA (0.33) | — | |
| Trichlorethanol SCHEMBL6898269 | 0.69 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093443-A | Good incorporation of higher alpha-olefins in copolymerization with ethylene | MOBIL OIL CORPORATION (US) | 1992-03-03 | — | — | US | claimed |
| JP-59141538-A | — | — | None | — | — | JP | disclosed |
| US-20220144730-A1 | Process for manufacture of 2,3-dichloro-1,1,1-trifluoropropane | FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) | 2022-05-12 | — | — | US | disclosed |
| US-20220127258-A1 | AROMATIC RING OR HETEROAROMATIC RING COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd. (CN) | 2022-04-28 | — | — | US | disclosed |
| CN-104710442-B | Diclofenac copper complex with anti-inflammatory activity and preparation method thereof | 山东理工大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-104693219-B | With Diclofenac copper complex for suppressing urease activity and preparation method thereof | 山东理工大学 | 2017-06-16 | — | — | CN | disclosed |
| EP-3087155-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | Albemarle Corporation (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160289527-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORP (US) | 2016-10-06 | — | — | US | disclosed |
| WO-2015100004-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORPORATION (US) | 2015-07-02 | — | — | WO | disclosed |
| EP-1780202-B1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-5356911-A | Hypotensive agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0332387-B1 | Triazole derivatives, their preparation and their use as fungicides | SANKYO CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5093443-A | Good incorporation of higher alpha-olefins in copolymerization with ethylene | MOBIL OIL CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0435627-A2 | Supported olefin polymerization catalyst | MOBIL OIL CORPORATION (US) | 1991-07-03 | — | — | EP | disclosed |
| US-4954470-A | Narrow molecular weight distribution | MOBIL OIL CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | disclosed |
| JP-S59141538-A | PRODUCTION OF HALOGENATED PROPIONIC ACID ESTER | AGENCY OF IND SCIENCE & TECHNOL | 1984-08-14 | — | — | JP | disclosed |