Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492218 | 0.88 | ACHE (0.49) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11492216 | 0.88 | ACHE (0.49) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11485774 | 0.86 | ACHE (0.43) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11485648 | 0.85 | ACHE (0.41) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11485656 | 0.85 | ACHE (0.41) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL10781080 | 0.84 | ACHE (0.48) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11459561 | 0.80 | ACHE (0.64) | ACHEBCHE | |
| SCHEMBL11459563 | 0.80 | ACHE (0.64) | ACHEBCHE | |
| SCHEMBL11485667 | 0.79 | BCHE (0.41) | ACHEBCHEHRH2CYP3A4CYP2D6 | |
| SCHEMBL11485664 | 0.79 | BCHE (0.41) | ACHEBCHEHRH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200578-A | ANTIULCER AGENTS, BLOCKING AGENTS, ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-04-29 | — | — | US | disclosed |