SCHEMBL11484010

SCHEMBL11484010

CC(O)c1ccc(Br)c(Br)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.48
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
NOX1 Q9Y5S8 1/20 0.37
RECQL P46063 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
KDM4E B2RXH2 4/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
ALOX15 P16050 2/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APEX1 P27695 1/20 0.36
MTOR P42345 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23693310 0.82 ALOX15 (0.48) UGT2B7KMT2AMEN1RECQLTDP1
SCHEMBL5941036 0.82 UGT2B7 (0.45) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL14966998 0.82 UGT2B7 (0.45) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL14966985 0.82 UGT2B7 (0.45) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL19667847 0.82 UGT2B7 (0.45) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL14967003 0.80 SLC6A2 (0.49) UGT2B7KMT2AMEN1NOX1MAPT
SCHEMBL8220975 0.80 UGT2B7 (0.44) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL7685001 0.80 UGT2B7 (0.44) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL14966853 0.80 UGT2B7 (0.44) UGT2B7KMT2AMEN1NOX1RECQL
SCHEMBL15921608 0.80 UGT2B7 (0.44) UGT2B7KMT2AMEN1NOX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4185992-A Imidazole derivatives MAY & BAKER LIMITED (GB) 1980-01-29 US disclosed