Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.51 |
| ▸ | ITGAL | P20701 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484142 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL11618539 | 0.88 | CYP1A2 (0.66) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL11618537 | 0.88 | CYP1A2 (0.66) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL1556455 | 0.87 | RAB9A (0.55) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL1556451 | 0.87 | RAB9A (0.55) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL1341697 | 0.85 | SMN1; SMN2 (0.69) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL1341698 | 0.85 | SMN1; SMN2 (0.69) | CYP1A2CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL11483281 | 0.83 | GPR183 (0.52) | MEN1KMT2AALDH1A1MAOBITGB2 | |
| SCHEMBL11483277 | 0.83 | GPR183 (0.52) | MEN1KMT2AALDH1A1MAOBITGB2 | |
| SCHEMBL2909561 | 0.82 | KMT2A (0.73) | CYP1A2CYP2C9MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189484-A | Antihypertensive quinazoline derivatives | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-19 | — | — | US | disclosed |