Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11178931 | 0.98 | AOC3 (0.35) | AOC3LMNAHTTALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL11187806 | 0.78 | LMNA (0.36) | AOC3LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21371965 | 0.72 | HTT (0.43) | LMNAHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11166356 | 0.71 | AOC3 (0.37) | AOC3HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL23689570 | 0.70 | SLC6A2 (0.42) | LMNAALDH1A1MAPTPOLBCYP3A4 | |
| SCHEMBL3424021 | 0.70 | SLC6A2 (0.42) | LMNAALDH1A1MAPTPOLBCYP3A4 | |
| SCHEMBL10031596 | 0.69 | CYP3A4 (0.44) | ALDH1A1KMT2AMEN1ALOX15SMN1; SMN2 | |
| SCHEMBL117057 | 0.69 | CYP3A4 (0.44) | ALDH1A1KMT2AMEN1ALOX15SMN1; SMN2 | |
| SCHEMBL17469429 | 0.69 | CYP3A4 (0.44) | ALDH1A1KMT2AMEN1ALOX15SMN1; SMN2 | |
| SCHEMBL11176553 | 0.69 | LMNA (0.45) | LMNAHTTALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188391-A | 4-[4-(Substituted)piperidino]quinazoline cardiac stimulants | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |