Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266681 | 0.89 | DRD2 (0.61) | KMT2ADRD2DRD3POLBMMP1 | |
| SCHEMBL7214216 | 0.85 | MEN1 (0.57) | KMT2AHSP90AA1POLBBCHEACHE | |
| SCHEMBL14256483 | 0.84 | DRD3 (0.65) | KMT2ADRD2DRD3POLBMMP1 | |
| SCHEMBL7220931 | 0.84 | KMT2A (0.59) | KMT2AHSP90AA1POLBBCHEACHE | |
| SCHEMBL9661477 | 0.83 | DRD2 (0.85) | KMT2ADRD2DRD3SMN1; SMN2LMNA | |
| SCHEMBL9661474 | 0.83 | DRD2 (0.85) | KMT2ADRD2DRD3SMN1; SMN2LMNA | |
| SCHEMBL15854247 | 0.81 | CYP3A4 (0.59) | KMT2ADRD2DRD3POLBSMN1; SMN2 | |
| SCHEMBL17219836 | 0.81 | CYP3A4 (0.59) | KMT2ADRD2DRD3POLBSMN1; SMN2 | |
| SCHEMBL11590847 | 0.81 | KMT2A (0.86) | KMT2APOLBMMP1MMP2MMP9 | |
| SCHEMBL15854249 | 0.80 | CYP3A4 (0.58) | KMT2ADRD2DRD3POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192883-A | ANTITUSSIVES | PIERRE FABRE, S.A. (FR) | 1980-03-11 | — | — | US | disclosed |
| US-4122199-A | Amides of pyrrolidinoethylamine which can be used in treatment of coughs | PIERRE FABRE S.A. (FR) | 1978-10-24 | — | — | US | disclosed |