Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467207 | 0.86 | HRH4 (0.51) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL11467205 | 0.86 | HRH4 (0.51) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL11158907 | 0.84 | HRH4 (0.50) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL7753798 | 0.81 | HRH4 (0.45) | HRH4HRH3HRH2 | |
| SCHEMBL7753802 | 0.81 | HRH4 (0.45) | HRH4HRH3HRH2 | |
| SCHEMBL11527371 | 0.80 | QPCT (0.51) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL11192767 | 0.79 | HRH4 (0.46) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL9777094 | 0.77 | QPCT (0.48) | HRH4QPCTHRH3LMNACYP3A4 | |
| SCHEMBL21064892 | 0.77 | KDM1A (0.64) | EPHX1CASP2KDM1AZDHHC20ZDHHC2 | |
| SCHEMBL11477577 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212875-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-15 | — | — | US | disclosed |