Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 7/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Buquineran SCHEMBL783795 | 0.89 | ENPP1 (0.60) | ENPP1MAPK1KDRPDGFRBACHE | |
| SCHEMBL20814063 | 0.87 | ENPP1 (0.68) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL22291145 | 0.84 | ENPP1 (0.69) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL11494695 | 0.80 | ENPP1 (0.59) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL4969179 | 0.80 | PDGFRB (0.69) | ENPP1MAPK1PDGFRBPDGFRA | |
| SCHEMBL22407367 | 0.79 | ENPP1 (0.70) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL11494694 | 0.79 | ENPP1 (0.61) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| Hydrochloric Acid SCHEMBL10797414 | 0.79 | ENPP1 (0.61) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL22291036 | 0.79 | ENPP1 (0.72) | ENPP1MAPK1PDGFRBACHEBACE1 | |
| SCHEMBL22455162 | 0.78 | ENPP1 (0.80) | ENPP1MAPK1ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188391-A | 4-[4-(Substituted)piperidino]quinazoline cardiac stimulants | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |