Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073030 | 0.79 | TSHR (0.45) | CNR2TSHRALDH1A1LMNATP53 | |
| SCHEMBL8744445 | 0.72 | ASAH1 (0.62) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL29145161 | 0.72 | ASAH1 (0.62) | TSHRALDH1A1LMNATP53CYP3A4 | |
| Biphenyl SCHEMBL17473067 | 0.72 | TSHR (0.62) | CNR2TSHRALDH1A1LMNATP53 | |
| Biphenyl SCHEMBL28032462 | 0.72 | TSHR (0.62) | CNR2TSHRALDH1A1LMNATP53 | |
| Biphenyl SCHEMBL17473024 | 0.72 | TSHR (0.62) | CNR2TSHRALDH1A1LMNATP53 | |
| Biphenyl SCHEMBL17473030 | 0.72 | TSHR (0.62) | CNR2TSHRALDH1A1LMNATP53 | |
| SCHEMBL16057185 | 0.70 | LMNA (0.53) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL14977311 | 0.70 | LMNA (0.53) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL16058203 | 0.70 | LMNA (0.53) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183752-A | DEVELOPMENT INHIBITOR RELEASING THIOETHERS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |