Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000039 | 0.90 | POLB (0.81) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL11374742 | 0.89 | KDM4E (0.65) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL4445314 | 0.88 | MRGPRX4 (0.60) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL4449372 | 0.87 | KDM4E (0.59) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL11494993 | 0.87 | POLB (0.58) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL5363217 | 0.86 | L3MBTL1 (0.61) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL22891351 | 0.85 | CYP1A2 (0.57) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL9152429 | 0.84 | KDM4E (0.81) | POLBKDM4EMRGPRX4LMNAGFER | |
| SCHEMBL4447285 | 0.83 | PTGER4 (0.62) | POLBKDM4EMRGPRX4LMNAL3MBTL1 | |
| SCHEMBL30775026 | 0.82 | KDM4E (0.77) | POLBKDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242121-A | USING A PHENOXYBENZOIC ACID, ITS ESTER OR SALT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-30 | — | — | US | claimed |
| EP-2842937-B1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| EP-2842937-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-4242121-A | USING A PHENOXYBENZOIC ACID, ITS ESTER OR SALT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | HLA-B, HLA-A, HLA-C | POLB 3333/4885KDM4E 1302/4885MRGPRX4 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.