SCHEMBL11486264

SCHEMBL11486264

CC1(C)CC2(CC(C)(C)N1CC1CO1)NC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.39
POLB P06746 1/20 0.37
EGLN1 Q9GZT9 2/20 0.36
EGLN3 Q9H6Z9 2/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
LMNA P02545 1/20 0.35
DHFR P00374 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
AR P10275 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11479183 0.81 KMT2A (0.51) ELANELMNASMN1; SMN2
SCHEMBL11476069 0.79 SMN1; SMN2 (0.36) POLBDHFRRAB9ASMN1; SMN2
SCHEMBL11483851 0.77 POLB (0.45) ELANEPOLBEGLN1EGLN3LMNA
SCHEMBL11483953 0.74 POLB (0.50) ELANEPOLBEGLN1EGLN3LMNA
SCHEMBL10124651 0.74 POLB (0.42) ELANEPOLBEGLN1EGLN3CACNA1B
SCHEMBL10124648 0.73 ELANE (0.41) ELANEPOLBEGLN1EGLN3LMNA
SCHEMBL11185462 0.73 CNR1 (0.39) RAB9ASMN1; SMN2
SCHEMBL11475745 0.73 SMN1; SMN2 (0.33) POLBLMNASMN1; SMN2
SCHEMBL11478004 0.73 TP53 (0.31) SMN1; SMN2
SCHEMBL11488057 0.73 POLB (0.49) POLBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US disclosed