SCHEMBL11475745

SCHEMBL11475745

CC1(C)CC2(CC(C)(C)N1CC1CO1)NC(=O)N(C1CCCCC1)C2=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.33
ALDH1A1 P00352 4/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 1/20 0.33
OPRM1 P35372 2/20 0.32
OPRL1 P41146 2/20 0.32
OPRK1 P41145 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TP53 P04637 2/20 0.31
CHRM3 P20309 1/20 0.31
HBB P68871 1/20 0.31
MAPK1 P28482 2/20 0.31
ACHE P22303 1/20 0.31
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
HSD11B1 P28845 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11475712 0.81 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A
SCHEMBL11476069 0.79 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1KMT2AOPRM1OPRL1
SCHEMBL11491674 0.79 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A
SCHEMBL11490575 0.77 CHRM3 (0.47) SMN1; SMN2ALDH1A1KMT2ACHRM3ACHE
SCHEMBL11488057 0.76 POLB (0.49) SMN1; SMN2ALDH1A1KMT2AL3MBTL1TP53
SCHEMBL11153950 0.74 LMNA (0.40) SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A
SCHEMBL11478004 0.73 TP53 (0.31) SMN1; SMN2TP53HBB
SCHEMBL11486264 0.73 ELANE (0.39) SMN1; SMN2LMNAPOLB
SCHEMBL11185462 0.73 CNR1 (0.39) SMN1; SMN2ALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL11143037 0.71 CNR1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US disclosed