Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494058 | 0.93 | LTB4R (0.50) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11769275 | 0.93 | LTB4R (0.53) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11765833 | 0.91 | LTB4R (0.61) | LTB4RAKR1B1LTB4R2TTRALDH1A1 | |
| SCHEMBL11486603 | 0.91 | AKR1B1 (0.50) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11766582 | 0.91 | AKR1B1 (0.52) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11769840 | 0.88 | AKR1B1 (0.53) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11766177 | 0.87 | LTB4R (0.52) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11766812 | 0.85 | LTB4R (0.59) | LTB4RAKR1B1LTB4R2TTRALDH1A1 | |
| SCHEMBL11772802 | 0.85 | KDM4E (0.54) | LTB4RAKR1B1LTB4R2TTRKDM4E | |
| SCHEMBL11769745 | 0.85 | LTB4R (0.53) | LTB4RAKR1B1LTB4R2TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217361-A | Disubstituted xanthone-2-carboxylic acid antiallergy agents | SYNTEX (U.S.A.) INC. (US) | 1980-08-12 | — | — | US | disclosed |