Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.77 |
| ▸ | DRD2 | P14416 | 6/20 | 0.77 |
| ▸ | DRD3 | P35462 | 6/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.77 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.77 |
| ▸ | HTR1A | P08908 | 3/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.77 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.77 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.77 |
| ▸ | HTR2A | P28223 | 2/20 | 0.77 |
| ▸ | HTR2B | P41595 | 2/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.77 |
| ▸ | HRH1 | P35367 | 1/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.77 |
| ▸ | DRD1 | P21728 | 4/20 | 0.62 |
| ▸ | DRD4 | P21917 | 4/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9857980 | 0.99 | ADRB2 (0.75) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11471245 | 0.95 | ADRB2 (0.85) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| Hydrochloric Acid SCHEMBL11400227 | 0.94 | ADRB2 (0.83) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11477204 | 0.90 | ADRB2 (0.70) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11471807 | 0.90 | ADRB2 (0.62) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11473050 | 0.89 | ADRB2 (0.85) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| Hydrochloric Acid SCHEMBL11472549 | 0.89 | ADRB2 (0.69) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11474447 | 0.89 | ADRB2 (0.72) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| Hydrochloric Acid SCHEMBL11472523 | 0.88 | ADRB2 (0.83) | ADRB2DRD2DRD3ADRA1AADRB1 | |
| SCHEMBL11473130 | 0.88 | ADRB2 (0.83) | ADRB2DRD2DRD3ADRA1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217305-A | HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-08-12 | — | — | US | disclosed |