Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451034 | 1.00 | LMNA (0.50) | LMNAMAPK1FABP3FABP4BLM | |
| SCHEMBL11443180 | 0.83 | LMNA (0.59) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL9000789 | 0.81 | LMNA (0.62) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL3601785 | 0.81 | LMNA (0.62) | LMNAMAPK1BLMNPSR1TSHR | |
| Hydrogen Peroxide SCHEMBL3271571 | 0.79 | FABP3 (0.52) | LMNAMAPK1FABP3FABP4TP53 | |
| Hydrogen Peroxide SCHEMBL3267226 | 0.79 | FABP3 (0.52) | LMNAMAPK1FABP3FABP4TP53 | |
| Hydrogen Peroxide SCHEMBL3271546 | 0.79 | FABP3 (0.52) | LMNAMAPK1FABP3FABP4TP53 | |
| Hydrogen Peroxide SCHEMBL11574983 | 0.79 | FABP3 (0.52) | LMNAMAPK1FABP3FABP4TP53 | |
| SCHEMBL7941836 | 0.79 | FABP3 (0.57) | LMNAMAPK1FABP3FABP4BLM | |
| SCHEMBL1573370 | 0.76 | LMNA (0.50) | LMNAMAPK1BLMNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |