Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091382 | 0.83 | PKM (0.81) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL11409261 | 0.81 | PKM (0.72) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL14593304 | 0.79 | PKM (0.79) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL12064248 | 0.75 | PKM (0.75) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL19532853 | 0.74 | PKM (0.72) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL24599226 | 0.73 | PKM (0.81) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8498720 | 0.73 | MAPT (1.00) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8499578 | 0.73 | MAPT (1.00) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL13002209 | 0.73 | PKM (0.62) | PKMTHRBHTTMAPTMEN1 | |
| SCHEMBL8499239 | 0.73 | MAPT (1.00) | PKMTHRBHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238622-A | D,L-2-Amino-4-(2-aminoethoxy)-trans-but-3-enoic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-12-09 | — | — | US | disclosed |