Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 11/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322181 | 0.91 | PNMT (0.83) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| Maleic Acid SCHEMBL11483377 | 0.89 | PNMT (0.80) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| Fumaric Acid SCHEMBL11483384 | 0.89 | PNMT (0.80) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL2401511 | 0.82 | PNMT (0.71) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL29941551 | 0.79 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL1885004 | 0.79 | PNMT (0.71) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL17056235 | 0.79 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL11483387 | 0.79 | PNMT (0.71) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL1487047 | 0.79 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL11483568 | 0.78 | PNMT (0.97) | PNMTADRA2AADRA2BADRA2CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228170-A | INHIBITOR OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE | SMITHKLINE CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |