Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408353 | 0.70 | HRH2 (0.31) | HRH2HRH1HRH4HRH3 | |
| SCHEMBL9428999 | 0.69 | — | — | |
| SCHEMBL2775 | 0.68 | GAA (0.37) | — | |
| SCHEMBL1401028 | 0.66 | — | — | |
| SCHEMBL12718363 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL5696107 | 0.66 | — | — | |
| SCHEMBL131092 | 0.64 | — | — | |
| SCHEMBL3424069 | 0.64 | DPP4 (0.57) | — | |
| SCHEMBL14395966 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL22856648 | 0.64 | CRBN (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242276-A | ACYLATION OF B-AMINOCROTONAMIDE BY DIMETHYLKETENE | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-12-30 | — | — | US | disclosed |