Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480851 | 1.00 | KDR (0.42) | KDRIKBKBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11481166 | 0.89 | SMN1; SMN2 (0.42) | IKBKBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11481617 | 0.85 | MAPT (0.35) | SMN1; SMN2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL11481297 | 0.84 | ALDH1A1 (0.34) | SMN1; SMN2KMT2ALMNACYP3A4MAPT | |
| SCHEMBL11480182 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL11481725 | 0.82 | GLA (0.33) | LMNACYP3A4MAPT | |
| SCHEMBL11473382 | 0.82 | MAPT (0.36) | SMN1; SMN2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL11481731 | 0.81 | GLA (0.32) | KMT2ALMNACYP3A4MAPT | |
| SCHEMBL11472552 | 0.81 | MAPT (0.35) | SMN1; SMN2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL11472446 | 0.81 | MAPT (0.35) | SMN1; SMN2KMT2ALMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235995-A | BACTERIOCIDES, PARASITICIDES, HERBICIDES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4066776-A | Anti-bacterial compositions containing certain 3-nitropyrazoles | ELI LILLY AND COMPANY (US) | 1978-01-03 | — | — | US | disclosed |