Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244401 | 0.84 | KMT2A (0.45) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11271692 | 0.83 | KMT2A (0.49) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11245898 | 0.83 | KMT2A (0.43) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11253499 | 0.81 | KMT2A (0.44) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11253460 | 0.81 | KMT2A (0.44) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11244375 | 0.81 | KMT2A (0.44) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11251510 | 0.81 | KMT2A (0.44) | KMT2ATRPV1OPRD1CYP2D6KCNH2 | |
| SCHEMBL11481865 | 0.81 | KMT2A (0.43) | KMT2ATRPV1OPRD1BACE1CTSD | |
| SCHEMBL11282992 | 0.80 | KMT2A (0.44) | KMT2ATRPV1OPRD1BACE1CTSD | |
| SCHEMBL11291814 | 0.79 | LMNA (0.48) | KMT2ATRPV1OPRD1BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |