Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426428 | 0.73 | TSHR (0.42) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL2198922 | 0.73 | TSHR (0.61) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL6171598 | 0.72 | TSHR (0.57) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL12426426 | 0.72 | ACHE (0.50) | TSHRNCEH1RAB9AMEN1KMT2A | |
| SCHEMBL2203331 | 0.71 | TSHR (0.60) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL10778554 | 0.71 | TSHR (0.68) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL8058246 | 0.71 | HRH3 (0.57) | TSHR | |
| SCHEMBL12426442 | 0.71 | TSHR (0.42) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL12426431 | 0.70 | TSHR (0.39) | TSHRNCEH1MEN1KMT2AALDH1A1 | |
| SCHEMBL16965607 | 0.70 | TSHR (0.58) | TSHRNCEH1PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4240965-A | TOXIC AGENTS FOR CHEMICAL WARFARE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1980-12-23 | — | — | US | disclosed |